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Known for its automotive industry and vibrant music scene, Detroit is a city of contrast waiting to be explored. Soak up the rich cultural life. Enjoy pure holiday shopping. Savor heavenly cuisine. Be a part of its vibrant nightlife. You will just love exploring Detroit. Plan your vacation with OneTravel cheap Detroit flights and enjoy a budget friendly vacation. With OneTravel you can grab exclusive deals on top airlines flying to Detroit including Delta Air Lines, Spirit Airlines and United Airlines. The average flight time from Myrtle Beach, SC to Detroit, MI is around two hours.