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A vibrant that has always been associated with science and technology, San Diego is a hip city with something for everyone. From the beautiful beaches to its one of a kind attraction, from its diverse cuisine to the vibrant nightlife, everything about San Diego is simply out of this world. Plan your trip with OneTravel cheap San Diego flights and save more on airline tickets. Fly with OneTravel exclusive airfare deals and get discounts on major airlines including Continental Airlines, Delta Air Lines and JetBlue Airways. The average flight time from Jacksonville, FL to San Diego, CA is around six hours and thirty minutes, including the layover time.